Mercedes-Benz S-Class
W2212007–2020
Compare the powertrains within this generation. Open a version to explore its specifications and equipment.
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- 02Model
- 03Generation
- 04Powertrain
- 05Equipment
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28 powertrains
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| Powertrain | Engine / motor | Power | Drivetrain | Explore & compare |
|---|---|---|---|---|
| amg s63 4matic ↗7-speed automatic · 2018–2019 | Gasoline · 5461.0 L · 577 hp | 577 hp | All-wheel drive | |
| amg s63 4matic convertible ↗7-speed automatic · 2018–2019 | Gasoline · 5461.0 L · 577 hp | 577 hp | All-wheel drive | |
| amg s63 4matic coupe ↗7-speed automatic · 2018–2019 | Gasoline · 5461.0 L · 577 hp | 577 hp | All-wheel drive | |
| amg s63 4matic plus ↗9-speed automatic · 2020–2020 | Gasoline · 3982.0 L · 603 hp | 603 hp | All-wheel drive | |
| amg s63 4matic plus convertible ↗9-speed automatic · 2020–2020 | Gasoline · 3982.0 L · 603 hp | 603 hp | All-wheel drive | |
| maybach s560 4matic ↗9-speed automatic · 2018–2019 | Gasoline · 3982.0 L · 463 hp | 463 hp | All-wheel drive | |
| maybach s650 ↗7-speed automatic · 2018–2020 | Gasoline · 5980.0 L · 621 hp | 621 hp | Rear-wheel drive | |
| s400 hybrid ↗7-speed automatic · 2010–2011 | Gasoline hybrid · 3500.0 L · 295 hp | 295 hp | Rear-wheel drive | |
| s550 ↗7-speed automatic · 2012–2016 | Gasoline · 4663.0 L · 449 hp | 449 hp | Rear-wheel drive | |
| s550 ↗7-speed automatic · 2007–2011 | Gasoline · 5500.0 L · 382 hp | 382 hp | Rear-wheel drive | |
| s550 4matic ↗7-speed automatic · 2007–2011 | Gasoline · 5500.0 L · 382 hp | 382 hp | All-wheel drive | |
| s550 4matic ↗7-speed automatic · 2012–2016 | Gasoline · 4663.0 L · 449 hp | 449 hp | All-wheel drive | |
| s550 4matic coupe ↗7-speed automatic · 2015–2016 | Gasoline · 4663.0 L · 449 hp | 449 hp | All-wheel drive | |
| s550 4matic coupe ↗7-speed automatic · 2017–2017 | Gasoline · 4663.0 L · 449 hp | 449 hp | All-wheel drive | |
| s550 convertible ↗7-speed automatic · 2017–2017 | Gasoline · 4663.0 L · 449 hp | 449 hp | Rear-wheel drive | |
| s550e ↗7-speed automatic · 2015–2017 | Gasoline plug-in hybrid · 2996.0 L · 436 hp | 436 hp | Rear-wheel drive | |
| s560 ↗9-speed automatic · 2018–2020 | Gasoline · 3982.0 L · 463 hp | 463 hp | Rear-wheel drive | |
| s560 4matic ↗9-speed automatic · 2018–2020 | Gasoline · 3982.0 L · 463 hp | 463 hp | All-wheel drive | |
| s560 4matic coupe ↗9-speed automatic · 2018–2021 | Gasoline · 3982.0 L · 463 hp | 463 hp | All-wheel drive | |
| s560 4matic maybach ↗9-speed automatic · 2020–2020 | Gasoline · 3982.0 L · 463 hp | 463 hp | All-wheel drive | |
| s560 convertible ↗9-speed automatic · 2018–2021 | Gasoline · 3982.0 L · 463 hp | 463 hp | Rear-wheel drive | |
| s600 ↗7-speed automatic · 2015–2017 | Gasoline · 5980.0 L · 523 hp | 523 hp | Rear-wheel drive | |
| s600 ↗5-speed automatic · 2003–2013 | Gasoline · 5513.0 L · 510 hp | 510 hp | Rear-wheel drive | |
| s63 amg ↗7-speed automatic · 2010–2013 | Gasoline · 6208.0 L · 518 hp | 518 hp | Rear-wheel drive | |
| s63 amg 4matic ↗7-speed automatic · 2016–2017 | Gasoline · 5461.0 L · 577 hp | 577 hp | All-wheel drive | |
| s63 amg 4matic coupe ↗7-speed automatic · 2016–2017 | Gasoline · 5461.0 L · 577 hp | 577 hp | All-wheel drive | |
| s65 amg ↗7-speed automatic · 2016–2020 | Gasoline · 5980.0 L · 621 hp | 621 hp | Rear-wheel drive | |
| s65 amg coupe ↗7-speed automatic · 2016–2019 | Gasoline · 5980.0 L · 621 hp | 621 hp | Rear-wheel drive |
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About this generation
The W221 continued the S-Class sedan with a more angular design, upgraded safety systems, and broader model coverage. It was sold in the U.S. throughout its run and included high-performance AMG versions.
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Catalog data disclaimer. Specifications and equipment are provided for reference and may be incomplete or vary by model year, market, version and optional packages. They do not confirm the configuration, condition or real-world performance of a specific vehicle. Verify relevant details with the manufacturer, vehicle documentation or seller before buying.